Management of primary cardiac leiomyosarcoma.

Background: Primary cardiac cancer is a rare event with various clinical presentations and often causes unexpected symptoms or sudden death. Case reports with this diagnosis are scarce. Case presentation: We present an unusual manifestation of leiomyosarcoma of the left atrium in a female patient, 33 years old. Presenting difficulty to walk, dyspnoea at rest, skin pallor, cough with hemoptoics and syncope. A transthoracic echocardiogram showed cavitary enlargement of the left atrium, moderate to significant mitral stenosis with an adherent mass in the anterior leaflet, left ventricular systolic function preserved at rest, and mild aortic and tricuspid insufficiency. The procedure was complete resection of the tumour or negative microscopic margins (R0 resection), 25 sessions of radiotherapy, 5 cycles of adjuvant chemotherapy using gemcitabine (900 mg/m2 on days 1 and 8) and docetaxel (75 mg/m2 on day 8), with a resolution of the clinical picture. After 5 years of follow-up, the patient had no metastases or recurrence of the initial tumour. Conclusion: The nonspecific symptoms presented in the reported case demonstrate that the cardiac tumour can mimic other cardiac disorders, such as coronary artery disease or pericarditis, rarely representing the first manifestation of a previously unknown malignancy.

Método Criativo Sensível na enfermagem: estudo bibliométrico / Sensitive Creative Method in nursing: bibliometric study / Método Creativo Sensible en enfermería: estudio bibliométrico

Objetivo: investigar a produção científica na área da enfermagem sobre o Método Criativo Sensível. Método: pesquisa descritiva, com abordagem quantitativa, do tipo revisão bibliométrica. Resultados: foram recuperados 293 documentos, dos quais 97 estão presentes na base de dados da Literatura Latino-Americana e do Caribe em Ciências da Saúde, 184 na Medical Literature Analysis and Retrieval System Online, seis na Scopus e seis na Web of Science. Em suma, destaca-se as publicações nos idiomas inglês (69,9%) e português (22,5%), bem como a disponibilidade no formato de artigos científicos (96,6%) entre os anos de 1967 a 2022. A revista Nurse Education detém 30 publicações. Os termos mais utilizados na indexação das pesquisas foram "Humanos", "Criatividade", "Métodos", "Psicologia" e "Ensino". Os principais autores na área foram Ivone Evangelista Cabral, Liliane Faria da Silva e Eliane Tatsch Neves. Conclusão: identificou-se crescimento do comportamento das informações sobre o método criativo sensível na enfermagem.

Objective: to investigate the scientific production in the area of nursing on the Sensitive Creative Method. Method: descriptive research, with a quantitative approach, of the bibliometric review type. Results: two hundred and ninety-three (293) documents were retrieved, of which 97 are present in the Latin American and Caribbean Health Sciences Literature database, 184 in the Medical Literature Analysis and Retrieval System Online, six in Scopus and six in the Web of Science. In short, publications in English (69.9%) and Portuguese (22.5%) stand out, as well as the availability in the format of scientific articles (96.6%) between 1967 and 2022. Nurse Education magazine owns 30 publications. The most used terms in the indexing of the searches were "Humans", "Creativity", "Methods", "Psychology" and "Teaching". The main authors in the area were Ivone Evangelista Cabral, Liliane Faria da Silva and Eliane Tatsch Neves. Conclusion: we identified an increase in the behavior of information about the sensitive creative method in nursing.

Objetivo: investigar la producción científica en el área de enfermería sobre el Método Creativo Sensible. Método: investigación descriptiva, con enfoque cuantitativo, del tipo revisión bibliométrica. Resultados: Se recuperaron 293 documentos, de los cuales 97 están presentes en la base de datos Literatura Latinoamericana y del Caribe en Ciencias de la Salud, 184 en el Sistema de Análisis y Recuperación de Literatura Médica en Línea, seis en Scopus y seis en Web of Science. En definitiva, destacan las publicaciones en inglés (69,9%) y portugués (22,5%), así como la disponibilidad en formato de artículos científicos (96,6%) entre los años 1967 a 2022. La revista Nurse Education cuenta con 30 publicaciones. Los términos más utilizados en las búsquedas de indexación fueron "Humanos", "Creatividad", "Métodos", "Psicología" y "Enseñanza". Las principales autoras del área fueron Ivone Evangelista Cabral, Liliane Faria da Silva y Eliane Tatsch Neves. Conclusión: se identificó crecimiento en el comportamiento de la información sobre el método creativo sensible en enfermería.

Impact of screening on cervical cancer incidence and mortality in a Northern Brazilian city.

Objective: To analyse the impact of screening actions on the incidence and mortality rates of cervical cancer (CC) in the city of Belém, Brazil. Methods: Based on the cancer registry data from 1998 to 2017, collected from the Belém Population-Based Cancer Registry, combined with local population data for the interval 1998-2017, CC incidence and mortality were calculated. The Segi world population 1960 was used for age-standardised incidence/mortality rates. Results: In the period analysed, there were 4,469 new cases and 1,660 deaths from CC. The median age at diagnosis of invasive cases was 51 years. The age-adjusted incidence rate decreased from 18.65/100,000 in 1998 to 11.79/100,000 in 2017, despite the increase observed in the first 5 years of the historical series, while there was stability in mortality rates in the same time lapse. Conclusion: CC is still one of the most common malignant tumours that threaten public health in northern Brazil. The trend of the disease depends on comprehensive prevention and control strategies regarding the local situation and age groups, with emphasis on the organisation of the screening programme and vaccination against human papillomavirus.

Incidence and mortality of myeloid malignancies in children, adolescents and Young adults in Brazil: A population-based study.

BACKGROUND: Myeloid malignancies (MM) are heterogeneous when it comes to incidence rates and pathogenesis. These variation rates are important to generate hypotheses on causal aetiology. This study aimed to describe incidence and mortality patterns of MM among children, adolescents and young adults (cAYA) in Brazil and to evaluate trends in incidence and mortality rate overtime. METHODS: Data were extracted from a dataset of 15 Population-based Cancer Registries located in five Brazilian geographical regions and calculated by age-specific, crude, and age-standardized incidence (ASR) and mortality rates per million persons. Joinpoint regression analyses were performed for trends evaluations, regionally. Annual Percent Change (APC) and Average Annual Percent Change (AAPC) were also estimated. RESULTS: The overall ASR for incidence and mortality of MM in Brazil was 14.57 and 8.83 per million, respectively. The AML (non-APL AML and APL) incidence rate is 8.18 per million, whereas other MM subtypes altogether have an incidence rate of 2.62 per million, and not otherwise specified (NOS) is 3.70 per million. The analysis of incidence trends (AAPC) showed a significant decline in Manaus (-5.6%) and São Paulo (-4.7%), and a significant increase was observed in Fortaleza (5.8%). Mortality trends steadily declined in all registries, with significant declines occurring in Goiânia (-1.5%), Belo Horizonte (-2.3%), São Paulo (-2.5%), Curitiba (-2.8%) and Porto Alegre (-4.1%). CONCLUSION: Our findings showed differences in the incidence and mortality rates of MM in cAYA in Brazil, geographically. Infants-AML have the highest incidence within the cAYA population (17.42 per million). There was a substantial decrease in mortality rate observed, which was interpreted as an improvement in MM recognition and therapeutic approach.